| Index | Knox City | Missouri | National |
| Average Test Scores | n/a | 44% | 48% |
| Student/Teacher ratio | n/a | 14:1 | 16:1 |
| Total public schools | n/a | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |

| Index | Knox City | Missouri | National |
| Completed 8th grade | 80.7% | 86.0% | 84.3% |
| Completed high school | 80.7% | 84.2% | 83.0% |
| Completed some college | 20.5% | 57.7% | 59.4% |
| Completed associate degree | 4.8% | 35.2% | 38.5% |
| Completed bachelors | 1.8% | 27.6% | 30.3% |
| Completed masters | 0.0% | 10.4% | 11.5% |
| Completed professional degree | 0.0% | 2.8% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Knox City. Using the proficiency score averages, the average test scores for Knox City, MO schools is n/a. The average student to teacher ratio is n/a. In Knox City, MO, an average of 80.7% of students have completed 8th grade and an average of 80.7% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Edina, MO | 1,284 | 43% | 9.9% |
| Lewistown, MO | 617 | 37% | 23.4% |
| Knox City, MO | 183 | n/a |
| City | Population | Avg. Test Scores | National Avg. |
| Howard, OH | 183 | 64% | 33.3% |
| Point Lay, AK | 183 | 10% | 79.2% |
| Patch Grove, WI | 183 | 41% | 14.6% |
| Vandervoort, AR | 184 | 50% | 3.1% |
| Malta Bend, MO | 182 | 35% | 27.1% |
| Knox City, MO | 183 | n/a |