| Index | Key Largo | Florida | National |
| Cost of living | 141 | 102 | 100 |
| Groceries | 100 | 102 | 100 |
| Health care | 103 | 104 | 100 |
| Housing | 226 | 97 | 100 |
| Transportation | 106 | 103 | 100 |
| Utilities | 114 | 110 | 100 |
| Lifestyle & Entertainment | 105 | 104 | 100 |
| Household Items | 100 | 102 | 100 |
| Education & Childcare | 110 | 106 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $111,546 | $9,296 | $2,603 | $3,347 |
| Renters | $84,721 | $7,060 | $1,977 | $2,542 |
| State | General Sales Tax | With Max Surtax |
| Florida | 6% | 7.5% |
| State | Income Tax (Low) | Income Tax (High) |
| Florida | 0% | 0% |
| City | Population | Cost of Living Index | National Avg. |
| Tavernier, FL | 2,025 | 150 | 49.5% |
| Islamorada, Village of Islands, FL | 6,530 | 170 | 69.7% |
| North Key Largo, FL | 904 | 328 | 228.0% |
| Key Largo, FL | 9,926 | 141 | 41.3% |
| City | Population | Cost of Living Index | National Avg. |
| Alexandria, KY | 9,927 | 97 | 2.8% |
| Oakville, CT | 9,928 | 113 | 12.8% |
| St. Francis, WI | 9,923 | 95 | 4.9% |
| Bristol, PA | 9,921 | 100 | 0.4% |
| Queens, NS | 9,932 | n/a | |
| Key Largo, FL | 9,926 | 141 | 41.3% |