| Index | Key Colony Beach | Florida | National |
| Cost of living | 154 | 102 | 100 |
| Groceries | 100 | 102 | 100 |
| Health care | 103 | 104 | 100 |
| Housing | 267 | 97 | 100 |
| Transportation | 106 | 103 | 100 |
| Utilities | 114 | 110 | 100 |
| Lifestyle & Entertainment | 105 | 104 | 100 |
| Household Items | 100 | 102 | 100 |
| Education & Childcare | 110 | 106 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $138,141 | $11,512 | $3,223 | $4,145 |
| Renters | $107,454 | $8,955 | $2,507 | $3,224 |
| State | General Sales Tax | With Max Surtax |
| Florida | 6% | 7.5% |
| State | Income Tax (Low) | Income Tax (High) |
| Florida | 0% | 0% |
| City | Population | Cost of Living Index | National Avg. |
| Layton, FL | 110 | 139 | 38.8% |
| Marathon, FL | 8,934 | 147 | 47.0% |
| Duck Key, FL | 780 | 246 | 146.3% |
| Key Colony Beach, FL | 543 | 154 | 53.6% |
| City | Population | Cost of Living Index | National Avg. |
| Strasburg, IL | 543 | 87 | 13.4% |
| Danville, MD | 543 | 94 | 6.2% |
| Bull Creek, MO | 543 | 79 | 21.5% |
| Urich, MO | 543 | 80 | 19.5% |
| Polkville, NC | 543 | 90 | 9.7% |
| Key Colony Beach, FL | 543 | 154 | 53.6% |