Holcomb, MO has a population of 684 and is the 17,616th largest city in the United States. The population density is 1,173 per sq mi which is 1258% higher than the Missouri average and 1195% higher than the national average. The median age in Holcomb is 36 which is approximately 5% lower than the Missouri average of 38. In Holcomb, 58% of the population over 15 years of age are married, 96% speak English and 2% speak Spanish. 73% of Holcomb residents were born in Missouri, 24% were born out of state, 0% were born outside of the United States and 3% were foreign born.