Guthrie, TX has a population of 147 and is the 25,734th largest city in the United States. The population density is 83 per sq mi which is 15% lower than the Texas average and 9% lower than the national average. The median age in Guthrie is 33 which is approximately 3% lower than the Texas average of 34. In Guthrie, 55% of the population over 15 years of age are married, 94% speak English and 6% speak Spanish. 82% of Guthrie residents were born in Texas, 18% were born out of state, 0% were born outside of the United States and 0% were foreign born.