Guadalupe, CA has a population of 7,252 and is the 5,050th largest city in the United States. The population density is 5,538 per sq mi which is 2283% higher than the California average and 6013% higher than the national average. The median age in Guadalupe is 29 which is approximately 20% lower than the California average of 36. In Guadalupe, 56% of the population over 15 years of age are married, 30% speak English and 67% speak Spanish. 61% of Guadalupe residents were born in California, 7% were born out of state, 0% were born outside of the United States and 33% were foreign born.