Guadalupe, AZ has a population of 6,172 and is the 5,649th largest city in the United States. The population density is 7,678 per sq mi which is 13256% higher than the Arizona average and 8375% higher than the national average. The median age in Guadalupe is 31 which is approximately 16% lower than the Arizona average of 37. In Guadalupe, 44% of the population over 15 years of age are married, 27% speak English and 67% speak Spanish. 78% of Guadalupe residents were born in Arizona, 13% were born out of state, 0% were born outside of the United States and 9% were foreign born.