| Index | East Prairie | Missouri | National |
| Cost of living | 80 | 88 | 100 |
| Goods & Services | 101 | 94 | 100 |
| Groceries | 95 | 96 | 100 |
| Health care | 94 | 100 | 100 |
| Housing | 44 | 77 | 100 |
| Transportation | 91 | 87 | 100 |
| Utilities | 88 | 92 | 100 |


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| Cost of living index | |
| Goods & Services index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $56,194 | $4,683 | $1,311 | $1,686 |
| Renters | $31,157 | $2,596 | $727 | $935 |
| State | General Sales Tax | With Max Surtax |
| Missouri | 4.225% | 10.85% |
| State | Income Tax (Low) | Income Tax (High) |
| Missouri | 2% | 4.95% |
| Item | East Prairie | National avg. | Difference |
| Haircut | $30.14 | $27.62 | 9.1% |
| Beauty Salon | $44.92 | $51.11 | 12.1% |
| Toothpaste | $4.09 | $4.09 | 0.1% |
| Shampoo | $1.45 | $1.54 | 6.0% |
| Movie | $14.38 | $12.88 | 11.7% |
| Yoga | $11.94 | $19.66 | 39.3% |
| Item | East Prairie | National avg. | Difference |
| Ground Beef | $8.00 | $7.70 | 3.8% |
| Fried Chicken | $1.47 | $1.66 | 11.6% |
| Milk | $4.57 | $4.73 | 3.4% |
| Potatoes | $5.54 | $5.26 | 5.4% |
| Pizza | $12.37 | $12.76 | 3.1% |
| Beer | $10.20 | $10.55 | 3.3% |
| Item | East Prairie | National avg. | Difference |
| Optometrist | $148.30 | $140.06 | 5.9% |
| Doctor | $125.28 | $153.82 | 18.6% |
| Dentist | $121.67 | $123.15 | 1.2% |
| Ibuprofen | $11.55 | $11.73 | 1.6% |
| Lipitor | $20.85 | $23.61 | 11.7% |
| Item | East Prairie | National avg. | Difference |
| Home Price | $118,061.00 | $326,622.00 | 63.9% |
| Avg. Mortgage Payment | $1,891.70 | $2,480.25 | 23.7% |
| Apartment Rent | $897.00 | $1,444.00 | 37.9% |
| Item | East Prairie | National avg. | Difference |
| Gasoline | $2.81 | $3.06 | 8.1% |
| Tire Balancing | $58.75 | $65.21 | 9.9% |
| Item | East Prairie | National avg. | Difference |
| All Electricity | $175.60 | $220.12 | 20.2% |
| Phone | $196.66 | $195.71 | 0.5% |
| City | Population | Cost of Living Index | National Avg. |
| North Lilbourn, MO | 191 | 92 | 8.1% |
| Pinhook, MO | 0 | 96 | 3.9% |
| Wilson City, MO | 24 | 75 | 24.7% |
| Wyatt, MO | 291 | 77 | 23.1% |
| Hickman, KY | 2,045 | 78 | 21.8% |
| East Prairie, MO | 3,072 | 80 | 19.6% |
| City | Population | Cost of Living Index | National Avg. |
| Hennessey, OK | 3,072 | 90 | 9.8% |
| Stanton, TX | 3,072 | 89 | 10.8% |
| Minburn County No. 27, AB | 3,072 | n/a | |
| Two Hills County No. 21, AB | 3,071 | n/a | |
| East Douglas, MA | 3,073 | 133 | 32.5% |
| East Prairie, MO | 3,072 | 80 | 19.6% |