De Soto, GA has a population of 303 and is the 22,444th largest city in the United States. The population density is 372 per sq mi which is 123% higher than the Georgia average and 310% higher than the national average. The median age in De Soto is 21 which is approximately 43% lower than the Georgia average of 36. In De Soto, 53% of the population over 15 years of age are married, 92% speak English and 8% speak Spanish. 88% of De Soto residents were born in Georgia, 7% were born out of state, 0% were born outside of the United States and 5% were foreign born.