De Pue, IL has a population of 1,661 and is the 12,110th largest city in the United States. The population density is 614 per sq mi which is 176% higher than the Illinois average and 577% higher than the national average. The median age in De Pue is 36 which is approximately 5% lower than the Illinois average of 37. In De Pue, 54% of the population over 15 years of age are married, 42% speak English and 58% speak Spanish. 65% of De Pue residents were born in Illinois, 8% were born out of state, 4% were born outside of the United States and 23% were foreign born.