Caruthersville, MO has a population of 5,941 and is the 5,789th largest city in the United States. The population density is 1,152 per sq mi which is 1233% higher than the Missouri average and 1171% higher than the national average. The median age in Caruthersville is 39 which is approximately 2% higher than the Missouri average of 38. In Caruthersville, 49% of the population over 15 years of age are married, 98% speak English and 2% speak Spanish. 63% of Caruthersville residents were born in Missouri, 37% were born out of state, 0% were born outside of the United States and 0% were foreign born.