Carlisle, OH has a population of 5,125 and is the 6,351st largest city in the United States. The population density is 1,448 per sq mi which is 462% higher than the Ohio average and 1499% higher than the national average. The median age in Carlisle is 41 which is approximately 3% higher than the Ohio average of 39. In Carlisle, 68% of the population over 15 years of age are married, 99% speak English and 0% speak Spanish. 83% of Carlisle residents were born in Ohio, 16% were born out of state, 0% were born outside of the United States and 1% were foreign born.