Carlisle, IA has a population of 4,031 and is the 7,417th largest city in the United States. The population density is 728 per sq mi which is 1232% higher than the Iowa average and 703% higher than the national average. The median age in Carlisle is 36 which is approximately 6% lower than the Iowa average of 38. In Carlisle, 62% of the population over 15 years of age are married, 99% speak English and 0% speak Spanish. 88% of Carlisle residents were born in Iowa, 10% were born out of state, 0% were born outside of the United States and 2% were foreign born.