Calhoun, MO has a population of 383 and is the 21,120th largest city in the United States. The population density is 389 per sq mi which is 351% higher than the Missouri average and 330% higher than the national average. The median age in Calhoun is 36 which is approximately 7% lower than the Missouri average of 38. In Calhoun, 56% of the population over 15 years of age are married, 99% speak English and 1% speak Spanish. 77% of Calhoun residents were born in Missouri, 22% were born out of state, 1% were born outside of the United States and 0% were foreign born.