| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 23°F | 48°F | 34°F | 2.4" |
| February | 25°F | 51°F | 37°F | 2.1" |
| March | 36°F | 63°F | 48°F | 3.8" |
| April | 45°F | 71°F | 57°F | 5.2" |
| May | 54°F | 78°F | 65°F | 5.9" |
| June | 64°F | 87°F | 75°F | 4.7" |
| July | 68°F | 91°F | 79°F | 4.3" |
| August | 66°F | 90°F | 77°F | 4.0" |
| September | 58°F | 83°F | 69°F | 5.4" |
| October | 46°F | 72°F | 58°F | 4.0" |
| November | 35°F | 61°F | 47°F | 3.2" |
| December | 26°F | 48°F | 36°F | 3.0" |
| Index | Buffalo | Missouri | National |
| Air quality index | 39 | 97 | 42 |
| Pollution index | 1,077,870 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 365 |
| Days with good air quality | 322 |
| Days with moderate air quality | 43 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.001% |
| Benzene | 0.020% |
| Carbon Tetrachloride | 0.002% |
| Lead | 0.000% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Bennett Springs, MO | 171 | 39 | 22.0% |
| Halfway, MO | 140 | 39 | 22.0% |
| Louisburg, MO | 53 | 39 | 22.0% |
| Pleasant Hope, MO | 668 | 39 | 22.0% |
| Conway, MO | 709 | 39 | 22.0% |
| Buffalo, MO | 3,101 | 39 | 22.0% |
| City | Population | Air Quality Index | National Avg. |
| Dunean, SC | 3,099 | 46 | 8.0% |
| Double Oak, TX | 3,099 | 51 | 2.0% |
| Houston, BC | 3,099 | n/a | |
| Homer, NY | 3,103 | 34 | 32.0% |
| Dover, FL | 3,098 | 43 | 14.0% |
| Buffalo, MO | 3,101 | 39 | 22.0% |
Here are the best places to live in Missouri
See the best places to live in & around Buffalo
Top 10 cities in Missouri with the best education system
10 Best cities in Missouri for employment