| Statistic | South End | Boston | Massachusetts |
| Population | 33,120 | 689,326 | 6,949,503 |
| Population density (sq mi) | 18,955 | 14,260 | 894 |
| Median age | 36.8 | 32.4 | 39.4 |
| Male/Female ratio | 0.9:1 | 0.9:1 | 0.9:1 |
| Married (15yrs & older) | n/a | 35% | 53% |
| Families w/ Kids under 18 | 37% | 39% | 43% |
| Speak English | n/a | 63% | 77% |
| Speak Spanish | n/a | 16% | 9% |


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| Race | South End | Boston | Massachusetts |
| White | 50.88% | 52.11% | 79.26% |
| Black | 14.67% | 24.20% | 7.26% |
| Asian | 17.78% | 9.82% | 6.11% |
| American Indian | 0.58% | 0.31% | 0.21% |
| Native Hawaiian | 0.05% | 0.05% | 0.03% |
| Mixed race | 5.54% | 7.25% | 3.01% |
| Other race | 10.50% | 6.26% | 4.13% |