| Index | Santa Anna | Texas | National |
| Average Test Scores | 47% | 47% | 48% |
| Student/Teacher ratio | 11:1 | 14:1 | 16:1 |
| Total public schools | 4 | 7,418 | 79,221 |
| Total private schools | n/a | 1,267 | 24,874 |
| Total post-secondary schools | n/a | 463 | 7,963 |

| Index | Santa Anna | Texas | National |
| Completed 8th grade | 75.0% | 79.3% | 84.3% |
| Completed high school | 74.0% | 77.8% | 83.0% |
| Completed some college | 36.8% | 57.3% | 59.4% |
| Completed associate degree | 10.8% | 34.9% | 38.5% |
| Completed bachelors | 6.9% | 28.1% | 30.3% |
| Completed masters | 1.3% | 9.6% | 11.5% |
| Completed professional degree | 0.0% | 2.6% | 3.3% |
| Completed doctorate | 0.0% | 1.1% | 1.3% |
There are a total of 4 public schools, n/a private schools and n/a post-secondary schools in Santa Anna. Using the proficiency score averages, the average test scores for Santa Anna, TX schools is 47%. The average student to teacher ratio is 11:1. In Santa Anna, TX, an average of 75.0% of students have completed 8th grade and an average of 74.0% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Bangs, TX | 1,559 | 44% | 8.0% |
| Coleman, TX | 4,425 | 41% | 15.6% |
| Santa Anna, TX | 1,118 | 47% | 2.1% |
| City | Population | Avg. Test Scores | National Avg. |
| Buffalo, IA | 1,118 | 70% | 44.8% |
| Bronson, FL | 1,118 | 46% | 4.7% |
| Rochelle, GA | 1,117 | 45% | 6.6% |
| Oakfield, WI | 1,119 | 51% | 5.2% |
| Lincoln, NH | 1,117 | 49% | 1.7% |
| Santa Anna, TX | 1,118 | 47% | 2.1% |