Sanctuary, TX has a population of 323 and is the 22,072nd largest city in the United States. The population density is 377 per sq mi which is 289% higher than the Texas average and 316% higher than the national average. The median age in Sanctuary is 35 which is approximately 3% higher than the Texas average of 34. In Sanctuary, 53% of the population over 15 years of age are married, 100% speak English and 0% speak Spanish. 57% of Sanctuary residents were born in Texas, 39% were born out of state, 3% were born outside of the United States and 1% were foreign born.