| Index | Prestonsburg | Kentucky | National |
| Income per capita | $19,849 | $24,802 | $29,829 |
| Median household income | $27,061 | $44,811 | $55,322 |
| Median income owner occupied | $55,385 | $56,922 | $70,586 |
| Median income renter occupied | $15,469 | $26,529 | $35,192 |
| Median earnings male | $35,099 | $32,723 | $36,919 |
| Median earnings female | $0 | $23,082 | $26,250 |
| Unemployment rate | 6.3% | 4.5% | 4.7% |
| Poverty level | 48.7% | 18.8% | 15.1% |


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| Labour Type | Male | Female |
| Construction industry | 6.8% | 6.8% |
| Manufacturing sector | 1.4% | 1.4% |
| Financial & insurance services | 10.3% | 10.3% |
| Wholesale & retail services | 10.3% | 10.3% |
| Public administration | 5.6% | 5.6% |
| Transportation, warehousing & utilities | 9.9% | 9.9% |
| Education, health & social services | 23.0% | 23.0% |
| Other | 30.9% | 30.9% |
| City | Population | Household Income | National Avg. |
| Auxier, KY | 917 | $69,223 | 25.1% |
| Dwale, KY | 192 | $54,006 | 2.4% |
| Inez, KY | 968 | $51,458 | 7.0% |
| Coal Run Village, KY | 1,319 | $44,167 | 20.2% |
| Pikeville, KY | 6,642 | $39,122 | 29.3% |
| Prestonsburg, KY | 3,537 | $27,061 | 51.1% |
| City | Population | Household Income | National Avg. |
| Ballville, OH | 3,537 | $66,814 | 20.8% |
| Campo, CA | 3,536 | $49,709 | 10.1% |
| Riverwoods, IL | 3,536 | $231,477 | 318.4% |
| Frontenac, MO | 3,538 | $174,676 | 215.7% |
| Marienville, PA | 3,538 | $35,278 | 36.2% |
| Prestonsburg, KY | 3,537 | $27,061 | 51.1% |