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| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 33°F | 66°F | 48°F | 0.8" |
| February | 35°F | 70°F | 52°F | 0.3" |
| March | 40°F | 76°F | 58°F | 0.4" |
| April | 45°F | 81°F | 63°F | 0.2" |
| May | 51°F | 88°F | 71°F | 0.1" |
| June | 63°F | 98°F | 81°F | 0.4" |
| July | 68°F | 94°F | 79°F | 5.0" |
| August | 65°F | 93°F | 77°F | 3.5" |
| September | 60°F | 90°F | 74°F | 2.4" |
| October | 50°F | 84°F | 66°F | 0.6" |
| November | 41°F | 76°F | 57°F | 0.3" |
| December | 34°F | 66°F | 48°F | 0.9" |
| Index | Patagonia | Arizona | National |
| Air quality index | 31 | 57 | 42 |
| Pollution index | 4,063,380 | 9,766,019 | 2,726,193 |
| Measurement | Total |
| Days measured | 362 |
| Days with good air quality | 280 |
| Days with moderate air quality | 80 |
| Days w/ poor A.Q. for sensitive groups | 2 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.004% |
| Benzene | 0.060% |
| Carbon Tetrachloride | 0.010% |
| Lead | 0.040% |
| Mercury | 0.001% |
| City | Population | Air Quality Index | National Avg. |
| Kino Springs, AZ | 302 | 31 | 38.0% |
| Nogales, AZ | 20,182 | 31 | 38.0% |
| Beyerville, AZ | 25 | 31 | 38.0% |
| Rio Rico, AZ | 19,948 | 31 | 38.0% |
| Elgin, AZ | 168 | 45 | 10.0% |
| Patagonia, AZ | 823 | 31 | 38.0% |
| City | Population | Air Quality Index | National Avg. |
| Weiner, AR | 823 | 45 | 10.0% |
| Council, ID | 823 | 36 | 28.0% |
| Brookport, IL | 823 | 44 | 12.0% |
| Hollow Creek, KY | 823 | 49 | 2.0% |
| Hightsville, NC | 823 | 34 | 32.0% |
| Patagonia, AZ | 823 | 31 | 38.0% |
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