| Index | O'Neill | Nebraska | National |
| Average Test Scores | 51% | 53% | 48% |
| Student/Teacher ratio | 6:1 | 13:1 | 16:1 |
| Total public schools | 8 | 780 | 79,221 |
| Total private schools | n/a | 182 | 24,874 |
| Total post-secondary schools | n/a | 56 | 7,963 |

| Index | O'Neill | Nebraska | National |
| Completed 8th grade | 88.6% | 88.4% | 84.3% |
| Completed high school | 86.5% | 87.2% | 83.0% |
| Completed some college | 55.6% | 63.7% | 59.4% |
| Completed associate degree | 36.8% | 40.1% | 38.5% |
| Completed bachelors | 22.8% | 30.0% | 30.3% |
| Completed masters | 7.1% | 9.9% | 11.5% |
| Completed professional degree | 2.5% | 2.9% | 3.3% |
| Completed doctorate | 1.3% | 1.2% | 1.3% |
There are a total of 8 public schools, n/a private schools and n/a post-secondary schools in O'Neill. Using the proficiency score averages, the average test scores for O'Neill, NE schools is 51%. The average student to teacher ratio is 6:1. In O'Neill, NE, an average of 88.6% of students have completed 8th grade and an average of 86.5% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| O'Neill, NE | 3,728 | 51% | 5.7% |
| City | Population | Avg. Test Scores | National Avg. |
| Watertown, CT | 3,726 | 55% | 13.5% |
| Lyman, SC | 3,732 | 50% | 3.6% |
| Toledo, OR | 3,733 | 35% | 28.1% |
| Lansing, NY | 3,722 | 69% | 43.1% |
| Centre, AL | 3,722 | 44% | 8.7% |
| O'Neill, NE | 3,728 | 51% | 5.7% |