| Statistic | O'Brien | Oregon | National |
| Population | 639 | 4,217,737 | 328,239,523 |
| Population density (sq mi) | 122 | 45 | 91 |
| Median age | 66.5 | 39.1 | 37.7 |
| Male/Female ratio | 0.6:1 | 1.0:1 | 1.0:1 |
| Married (15yrs & older) | 67% | 55% | 55% |
| Families w/ Kids under 18 | 0% | 42% | 43% |
| Speak English | 100% | 85% | 79% |
| Speak Spanish | 0% | 9% | 13% |
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| Race | O'Brien | Oregon | National |
| White | 89.51% | 85.07% | 73.35% |
| Black | 0.00% | 1.86% | 12.63% |
| Asian | 0.00% | 4.02% | 5.22% |
| American Indian | 10.49% | 1.14% | 0.82% |
| Native Hawaiian | 0.00% | 0.38% | 0.18% |
| Mixed race | 0.00% | 4.41% | 3.06% |
| Other race | 0.00% | 3.13% | 4.75% |
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