| Index | Mission | South Dakota | National |
| Average Test Scores | 18% | 48% | 48% |
| Student/Teacher ratio | n/a | 14:1 | 16:1 |
| Total public schools | n/a | 340 | 79,221 |
| Total private schools | n/a | 76 | 24,874 |
| Total post-secondary schools | n/a | 25 | 7,963 |
| Index | Mission | South Dakota | National |
| Completed 8th grade | 81.8% | 89.1% | 84.3% |
| Completed high school | 80.4% | 86.8% | 83.0% |
| Completed some college | 61.9% | 60.4% | 59.4% |
| Completed associate degree | 31.3% | 38.5% | 38.5% |
| Completed bachelors | 20.4% | 27.5% | 30.3% |
| Completed masters | 7.6% | 8.1% | 11.5% |
| Completed professional degree | 3.8% | 2.5% | 3.3% |
| Completed doctorate | 1.0% | 1.2% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Mission. Using the proficiency score averages, the average test scores for Mission, SD schools is 18%. The average student to teacher ratio is n/a. In Mission, SD, an average of 81.8% of students have completed 8th grade and an average of 80.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Wood, SD | 57 | 50% | 4.2% |
| Okreek, SD | 230 | 20% | 58.3% |
| Rosebud, SD | 2,144 | 10% | 79.2% |
| St. Francis, SD | 544 | 3% | 93.8% |
| Mission, SD | 1,455 | 18% | 62.8% |
| City | Population | Avg. Test Scores | National Avg. |
| Wheaton, MN | 1,455 | 62% | 29.2% |
| Atkinson, NE | 1,454 | 63% | 31.3% |
| Louisville, NE | 1,456 | 60% | 24.3% |
| Pleasureville, KY | 1,456 | 47% | 2.1% |
| Ash Grove, MO | 1,457 | 48% | 0.5% |
| Mission, SD | 1,455 | 18% | 62.8% |
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