| Statistic | Matlacha | Florida | National |
| Average one way commute | 24min | 27min | 26min |
| Workers who drive to work | 76.2% | 79.5% | 76.4% |
| Workers who carpool | 0.0% | 9.3% | 9.3% |
| Workers who take public transit | 0.0% | 2.1% | 5.1% |
| Workers who bicycle | 0.0% | 0.7% | 0.6% |
| Workers who walk | 14.5% | 1.5% | 2.8% |
| Working from home | 9.2% | 5.4% | 4.6% |
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