| Index | Matlacha | Florida | National |
| Income per capita | $109,470 | $40,554 | $44,883 |
| Median household income | $88,877 | $72,078 | $81,333 |
| Median income owner occupied | $0 | $88,075 | $106,172 |
| Median income renter occupied | $56,237 | $51,794 | $52,080 |
| Median earnings male | $369,861 | $45,688 | $54,343 |
| Median earnings female | $23,388 | $37,493 | $38,439 |
| Unemployment rate | 3.8% | 5.2% | 4.9% |
| Poverty level | 10.6% | 16.1% | 15.1% |
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| Labour Type | Male | Female |
| Construction industry | 4.0% | 4.0% |
| Manufacturing sector | 4.5% | 4.5% |
| Financial & insurance services | 16.1% | 16.1% |
| Wholesale & retail services | 5.4% | 5.4% |
| Public administration | 0.0% | 0.0% |
| Transportation, warehousing & utilities | 0.0% | 0.0% |
| Education, health & social services | 8.5% | 8.5% |
| Other | 61.4% | 61.4% |
| City | Population | Household Income | National Avg. |
| Sanibel, FL | 7,660 | $137,514 | 69.1% |
| Burnt Store Marina, FL | 2,216 | $135,238 | 66.3% |
| Whiskey Creek, FL | 5,657 | $114,737 | 41.1% |
| Fort Myers Beach, FL | 7,313 | $113,689 | 39.8% |
| Lochmoor Waterway Estates, FL | 5,159 | $111,192 | 36.7% |
| Matlacha, FL | 872 | $88,877 | 9.3% |
| City | Population | Household Income | National Avg. |
| Black Rock, AR | 872 | $71,444 | 12.2% |
| Cleone, CA | 872 | $125,016 | 53.7% |
| Ventress, LA | 872 | $74,491 | 8.4% |
| Freeport, MN | 872 | $110,853 | 36.3% |
| Hankinson, ND | 872 | $89,431 | 10.0% |
| Matlacha, FL | 872 | $88,877 | 9.3% |
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