| Index | Lower Brule | South Dakota | National |
| Income per capita | $14,628 | $41,166 | $44,883 |
| Median household income | $39,406 | $77,914 | $81,333 |
| Median income owner occupied | $0 | $100,475 | $106,172 |
| Median income renter occupied | $35,017 | $45,187 | $52,080 |
| Median earnings male | $38,312 | $52,540 | $54,343 |
| Median earnings female | $29,635 | $36,073 | $38,439 |
| Unemployment rate | 10.4% | 2.9% | 4.9% |
| Poverty level | 47.9% | 14.0% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 10.9% | 10.9% |
| Manufacturing sector | 0.0% | 0.0% |
| Financial & insurance services | 0.0% | 0.0% |
| Wholesale & retail services | 5.0% | 5.0% |
| Public administration | 12.6% | 12.6% |
| Transportation, warehousing & utilities | 7.6% | 7.6% |
| Education, health & social services | 23.5% | 23.5% |
| Other | 40.3% | 40.3% |
| City | Population | Household Income | National Avg. |
| Kennebec, SD | 357 | $93,749 | 15.3% |
| Reliance, SD | 113 | $81,554 | 0.3% |
| Fort Thompson, SD | 1,300 | $24,485 | 69.9% |
| Lower Brule, SD | 1,002 | $39,406 | 51.5% |
| City | Population | Household Income | National Avg. |
| Selma, IN | 1,002 | $70,459 | 13.4% |
| Spearville, KS | 1,002 | $92,947 | 14.3% |
| Lake Shore, MN | 1,002 | $147,681 | 81.6% |
| Dortches, NC | 1,002 | $96,184 | 18.3% |
| Amenia, NY | 1,002 | $96,330 | 18.4% |
| Lower Brule, SD | 1,002 | $39,406 | 51.5% |