Lake City, FL has a population of 12,137 and is the 3,386th largest city in the United States. The population density is 1,007 per sq mi which is 243% higher than the Florida average and 1012% higher than the national average. The median age in Lake City is 38 which is approximately 9% lower than the Florida average of 42. In Lake City, 43% of the population over 15 years of age are married, 91% speak English and 6% speak Spanish. 61% of Lake City residents were born in Florida, 33% were born out of state, 2% were born outside of the United States and 4% were foreign born.