| Statistic | San Marco | Jacksonville | Florida |
| Population | 2,451 | 934,752 | 21,997,150 |
| Population density (sq mi) | 3,384 | 1,250 | 410 |
| Median age | 42.4 | 35.9 | 41.6 |
| Male/Female ratio | 0.9:1 | 0.9:1 | 1.0:1 |
| Married (15yrs & older) | n/a | 49% | 54% |
| Families w/ Kids under 18 | 49% | 42% | 38% |
| Speak English | n/a | 85% | 72% |
| Speak Spanish | n/a | 7% | 21% |
| Race | San Marco | Jacksonville | Florida |
| White | 73.53% | 56.28% | 75.90% |
| Black | 16.67% | 30.88% | 16.14% |
| Asian | 6.63% | 4.83% | 2.61% |
| American Indian | 0.00% | 0.21% | 0.27% |
| Native Hawaiian | 0.00% | 0.07% | 0.06% |
| Mixed race | 3.01% | 5.15% | 2.48% |
| Other race | 0.16% | 2.57% | 2.54% |
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