| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 43°F | 68°F | 55°F | 4.2" |
| February | 43°F | 69°F | 55°F | 3.8" |
| March | 48°F | 75°F | 61°F | 3.4" |
| April | 55°F | 81°F | 68°F | 2.6" |
| May | 62°F | 87°F | 74°F | 3.5" |
| June | 70°F | 90°F | 79°F | 6.3" |
| July | 72°F | 91°F | 80°F | 6.4" |
| August | 73°F | 91°F | 80°F | 7.9" |
| September | 69°F | 89°F | 77°F | 2.5" |
| October | 61°F | 83°F | 70°F | 4.4" |
| November | 49°F | 74°F | 61°F | 1.3" |
| December | 47°F | 71°F | 58°F | 3.9" |
| Index | Interlachen | Florida | National |
| Air quality index | 17 | 35 | 42 |
| Pollution index | 5,184,880 | 7,570,785 | 2,726,193 |
| Measurement | Total |
| Days measured | 352 |
| Days with good air quality | 347 |
| Days with moderate air quality | 5 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.190% |
| Benzene | 0.060% |
| Carbon Tetrachloride | 0.070% |
| Lead | 0.060% |
| Mercury | 0.050% |
| City | Population | Air Quality Index | National Avg. |
| Palatka, FL | 10,407 | 17 | 66.0% |
| Welaka, FL | 614 | 17 | 66.0% |
| Hawthorne, FL | 1,711 | 35 | 30.0% |
| Keystone Heights, FL | 1,530 | 35 | 30.0% |
| Interlachen, FL | 1,686 | 17 | 66.0% |
| City | Population | Air Quality Index | National Avg. |
| Lincolnton, GA | 1,686 | 47 | 6.0% |
| Cricket, NC | 1,686 | 26 | 48.0% |
| Pleasant Grove, OH | 1,686 | 41 | 18.0% |
| Evadale, TX | 1,686 | 45 | 10.0% |
| Westwood, CA | 1,685 | 46 | 8.0% |
| Interlachen, FL | 1,686 | 17 | 66.0% |
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