| Index | Guthrie | Kentucky | National |
| Average Test Scores | 61% | 48% | 48% |
| Student/Teacher ratio | 14:1 | 16:1 | 16:1 |
| Total public schools | 1 | 1,157 | 79,221 |
| Total private schools | 1 | 298 | 24,874 |
| Total post-secondary schools | n/a | 130 | 7,963 |

| Index | Guthrie | Kentucky | National |
| Completed 8th grade | 74.3% | 81.0% | 84.3% |
| Completed high school | 70.5% | 77.8% | 83.0% |
| Completed some college | 31.9% | 51.3% | 59.4% |
| Completed associate degree | 13.0% | 30.5% | 38.5% |
| Completed bachelors | 7.1% | 22.7% | 30.3% |
| Completed masters | 2.4% | 9.3% | 11.5% |
| Completed professional degree | 0.0% | 2.6% | 3.3% |
| Completed doctorate | 0.0% | 0.9% | 1.3% |
There are a total of 1 public schools, 1 private schools and n/a post-secondary schools in Guthrie. Using the proficiency score averages, the average test scores for Guthrie, KY schools is 61%. The average student to teacher ratio is 14:1. In Guthrie, KY, an average of 74.3% of students have completed 8th grade and an average of 70.5% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Clarksville, TN | 160,664 | 44% | 7.4% |
| Pembroke, KY | 742 | 44% | 9.4% |
| Elkton, KY | 2,133 | 43% | 11.1% |
| Cedar Hill, TN | 276 | 29% | 39.6% |
| Guthrie, KY | 1,350 | 61% | 26.0% |
| City | Population | Avg. Test Scores | National Avg. |
| Thorndale, TX | 1,350 | 43% | 9.7% |
| Minneota, MN | 1,350 | 72% | 50.0% |
| Olivet, NJ | 1,350 | 54% | 11.5% |
| Buffalo, OK | 1,349 | 20% | 58.9% |
| Bethany, IL | 1,351 | 14% | 71.4% |
| Guthrie, KY | 1,350 | 61% | 26.0% |