| Index | Depew | New York | National |
| Income per capita | $49,603 | $51,391 | $44,883 |
| Median household income | $92,711 | $89,985 | $81,333 |
| Median income owner occupied | $109,572 | $125,982 | $106,172 |
| Median income renter occupied | $60,498 | $58,659 | $52,080 |
| Median earnings male | $67,553 | $59,465 | $54,343 |
| Median earnings female | $52,539 | $44,739 | $38,439 |
| Unemployment rate | 3.9% | 5.0% | 4.9% |
| Poverty level | 7.2% | 15.5% | 15.1% |

| Labour Type | Male | Female |
| Construction industry | 7.2% | 7.2% |
| Manufacturing sector | 22.5% | 22.5% |
| Financial & insurance services | 3.8% | 3.8% |
| Wholesale & retail services | 14.3% | 14.3% |
| Public administration | 6.2% | 6.2% |
| Transportation, warehousing & utilities | 9.2% | 9.2% |
| Education, health & social services | 11.4% | 11.4% |
| Other | 24.4% | 24.4% |
| City | Population | Household Income | National Avg. |
| Clarence Center, NY | 3,300 | $175,860 | 116.2% |
| Elma Center, NY | 3,902 | $140,353 | 72.6% |
| Orchard Park, NY | 3,242 | $138,484 | 70.3% |
| Harris Hill, NY | 6,197 | $126,828 | 55.9% |
| Town Line, NY | 1,821 | $126,594 | 55.6% |
| Depew, NY | 15,627 | $92,711 | 14.0% |
| City | Population | Household Income | National Avg. |
| Salida, CA | 15,629 | $122,008 | 50.0% |
| Mastic, NY | 15,624 | $140,194 | 72.4% |
| Berea, SC | 15,623 | $55,805 | 31.4% |
| Ladson, SC | 15,636 | $93,582 | 15.1% |
| Bellair-Meadowbrook Terrace, FL | 15,617 | $73,632 | 9.5% |
| Depew, NY | 15,627 | $92,711 | 14.0% |