| Index | Defiance | Missouri | National |
| Income per capita | $50,200 | $27,044 | $29,829 |
| Median household income | $0 | $49,593 | $55,322 |
| Median income owner occupied | $0 | $62,242 | $70,586 |
| Median income renter occupied | $0 | $30,016 | $35,192 |
| Median earnings male | $0 | $34,901 | $36,919 |
| Median earnings female | $46,250 | $24,771 | $26,250 |
| Unemployment rate | 0.0% | 4.1% | 4.7% |
| Poverty level | 0.0% | 15.3% | 15.1% |


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| Labour Type | Male | Female |
| Construction industry | 0.0% | 0.0% |
| Manufacturing sector | 0.0% | 0.0% |
| Financial & insurance services | 0.0% | 0.0% |
| Wholesale & retail services | 64.0% | 64.0% |
| Public administration | 36.0% | 36.0% |
| Transportation, warehousing & utilities | 0.0% | 0.0% |
| Education, health & social services | 0.0% | 0.0% |
| Other | 0.0% | 0.0% |
| City | Population | Household Income | National Avg. |
| Clarkson Valley, MO | 2,619 | $208,000 | 276.0% |
| Weldon Spring Heights, MO | 120 | $147,083 | 165.9% |
| Innsbrook, MO | 843 | $143,500 | 159.4% |
| Wildwood, MO | 35,476 | $135,177 | 144.3% |
| Dardenne Prairie, MO | 13,385 | $134,267 | 142.7% |
| Defiance, MO | 68 | $0 | 100.0% |
| City | Population | Household Income | National Avg. |
| Ekwok, AK | 68 | $32,917 | 40.5% |
| Union Grove, AL | 68 | $0 | 100.0% |
| Anthonyville, AR | 68 | $20,000 | 63.8% |
| Marie, AR | 68 | $41,250 | 25.4% |
| Keddie, CA | 68 | $110,000 | 98.8% |
| Defiance, MO | 68 | $0 | 100.0% |