| Statistic | De Pere | Wisconsin | National |
| Population | 25,789 | 5,966,344 | 336,919,644 |
| Population density (sq mi) | 2,217 | 110 | 91 |
| Median age | 34.4 | 39.1 | 37.7 |
| Male/Female ratio | 0.9:1 | 1.0:1 | 1.0:1 |
| Married (15yrs & older) | 54% | 57% | 55% |
| Families w/ Kids under 18 | 48% | 43% | 43% |
| Speak English | 95% | 91% | 79% |
| Speak Spanish | 1% | 5% | 13% |

The demographics of De Pere offer invaluable insights into the composition, dynamics and needs of both urban and rural areas, empowering planners, developers and policymakers to foster prosperity, equity, and well-being for all residents. With a population of 25,789, De Pere exhibits a population density of 2,217 people per square mile, contrasting with the national average of 91. The median age stands at 34.4, with 54% of individuals aged 15 or older being married and 48% having children under 18. In terms of income equality in De Pere, 11% of households report a median income below $25,000, while 16% report an income exceeding $150,000, showcasing a diverse economic landscape.
The 5 largest ethnic groups in De Pere are 91.3% White, 0.5% Black or African American, 3.2% Asian, 2.3% American Indian and 0% Native Hawaiian, with 1.5% of the population identifying as Hispanic or Latino. Of note, 95.4% of households reported speaking English only, while 1% reported speaking Spanish only. Additionally, 3.5% of residents were classified as foreign-born. The De Pere racial demographics and ethnicity breakdown are essential for comprehending and addressing systemic inequities, advancing social justice and inclusion and cultivating resilient communities.
The De Pere population density comes in at 2,217 people per square mile, which makes it one of the most densely populated areas in the country, far surpassing the national average of 91. Areas characterized by high population density often boast an abundance of amenities and services within close proximity, providing residents with convenient access to healthcare, education, cultural attractions, dining establishments, retail outlets and transportation options. This accessibility could potentially enhance residents' overall quality of life and well-being.
Social Cohesion: The reporting and analysis of demographics are essential for fostering social cohesion and understanding among diverse communities. By acknowledging and valuing differences in De Pere demographics, societies can champion inclusivity, diversity and social harmony while tackling social disparities and advocating for equal opportunities. Racial demographics showcase the varied makeup of a population and play a vital role in nurturing inclusive and hospitable communities. Embracing diversity bolsters social cohesion, enhances cultural comprehension and enriches society by honoring the contributions of individuals from diverse racial and ethnic backgrounds.
Urban Development: De Pere demographic statistics are invaluable for urban planners in designing and developing areas that cater to residents' needs, encompassing housing, transportation, and public services, all while fostering sustainability and enhancing quality of life. Shifts in demographics can influence gentrification and neighborhood transformation, whether in urban or rural settings. As neighborhoods attract new residents with varying income levels and lifestyle preferences, property values may increase, potentially displacing long-term residents and altering the neighborhood's character. Analyzing population density, age distribution, household size, and income levels is crucial for guiding decisions regarding zoning, transportation infrastructure, housing expansion and public amenities. Utilizing De Pere demographic data in planning and executing affordable housing initiatives can serve as a preventive measure against displacement.
Healthcare Planning: By analyzing the De Pere demographic data, it can potentially inform healthcare planning and delivery by identifying population health needs, disparities, and risk factors. Understanding demographic trends helps healthcare providers and policymakers allocate resources, develop prevention and intervention programs, and address health inequities within communities. By leveraging demographic data, healthcare providers and policymakers can work towards achieving equitable, accessible, and high-quality healthcare for all individuals and communities. This proactive approach to healthcare planning ensures that interventions are targeted, resources are allocated efficiently, and healthcare services are tailored to meet the diverse needs of populations.
| Race | De Pere | Wisconsin | National |
| White | 91.29% | 86.21% | 73.35% |
| Black | 0.53% | 6.29% | 12.63% |
| Asian | 3.23% | 2.57% | 5.22% |
| American Indian | 2.34% | 0.89% | 0.82% |
| Native Hawaiian | 0.02% | 0.02% | 0.18% |
| Mixed race | 2.38% | 2.19% | 3.06% |
| Other race | 0.21% | 1.83% | 4.75% |