| Index | Clayton | Missouri | National |
| Average Test Scores | 73% | 44% | 48% |
| Student/Teacher ratio | 17:1 | 14:1 | 16:1 |
| Total public schools | 7 | 1,899 | 79,221 |
| Total private schools | 2 | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |


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| Index | Clayton | Missouri | National |
| Completed 8th grade | 95.7% | 86.0% | 84.3% |
| Completed high school | 95.2% | 84.2% | 83.0% |
| Completed some college | 90.4% | 57.7% | 59.4% |
| Completed associate degree | 80.7% | 35.2% | 38.5% |
| Completed bachelors | 78.7% | 27.6% | 30.3% |
| Completed masters | 45.4% | 10.4% | 11.5% |
| Completed professional degree | 22.3% | 2.8% | 3.3% |
| Completed doctorate | 9.1% | 1.2% | 1.3% |
There are a total of 7 public schools, 2 private schools and n/a post-secondary schools in Clayton. Using the proficiency score averages, the average test scores for Clayton, MO schools is 73%. The average student to teacher ratio is 17:1. In Clayton, MO, an average of 95.7% of students have completed 8th grade and an average of 95.2% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Brentwood, MO | 8,283 | 70% | 45.6% |
| Olivette, MO | 8,079 | 70% | 44.8% |
| Chesterfield, MO | 48,902 | 69% | 43.2% |
| Kirkwood, MO | 28,511 | 69% | 43.1% |
| Webster Groves, MO | 23,373 | 64% | 32.8% |
| Clayton, MO | 17,205 | 73% | 52.7% |
| City | Population | Avg. Test Scores | National Avg. |
| Cohoes, NY | 17,198 | 52% | 8.5% |
| Danville, KY | 17,223 | 55% | 13.5% |
| Dallas, OR | 17,229 | 39% | 18.8% |
| Easton, MD | 17,240 | 37% | 22.2% |
| Sikeston, MO | 17,170 | 34% | 30.2% |
| Clayton, MO | 17,205 | 73% | 52.7% |