| Index | Chillicothe | Missouri | National |
| Income per capita | $32,505 | $39,715 | $44,883 |
| Median household income | $66,671 | $72,613 | $81,333 |
| Median income owner occupied | $76,754 | $90,986 | $106,172 |
| Median income renter occupied | $52,629 | $45,210 | $52,080 |
| Median earnings male | $50,853 | $52,324 | $54,343 |
| Median earnings female | $38,369 | $36,971 | $38,439 |
| Unemployment rate | 2.0% | 4.4% | 4.9% |
| Poverty level | 16.0% | 15.3% | 15.1% |


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| Labour Type | Male | Female |
| Construction industry | 7.8% | 7.8% |
| Manufacturing sector | 18.0% | 18.0% |
| Financial & insurance services | 0.4% | 0.4% |
| Wholesale & retail services | 19.3% | 19.3% |
| Public administration | 8.7% | 8.7% |
| Transportation, warehousing & utilities | 8.2% | 8.2% |
| Education, health & social services | 11.3% | 11.3% |
| Other | 25.1% | 25.1% |
| City | Population | Household Income | National Avg. |
| Mooresville, MO | 138 | $97,118 | 19.4% |
| Utica, MO | 230 | $96,052 | 18.1% |
| Meadville, MO | 571 | $87,849 | 8.0% |
| Lock Springs, MO | 41 | $86,940 | 6.9% |
| Braymer, MO | 678 | $69,798 | 14.2% |
| Chillicothe, MO | 9,377 | $66,671 | 18.0% |
| City | Population | Household Income | National Avg. |
| Yorkshire, VA | 9,373 | $107,308 | 31.9% |
| Seven Corners, VA | 9,382 | $95,716 | 17.7% |
| Summit View, WA | 9,371 | $118,660 | 45.9% |
| Comox Valley C (Puntledge - Black Creek), BC | 9,371 | n/a | |
| Coaldale, AB | 9,383 | n/a | |
| Chillicothe, MO | 9,377 | $66,671 | 18.0% |