| Index | Chillicothe | Missouri | National |
| Cost of living | 84 | 90 | 100 |
| Groceries | 97 | 96 | 100 |
| Health care | 97 | 97 | 100 |
| Housing | 56 | 77 | 100 |
| Transportation | 96 | 96 | 100 |
| Utilities | 95 | 95 | 100 |
| Lifestyle & Entertainment | 96 | 95 | 100 |
| Household Items | 99 | 97 | 100 |
| Education & Childcare | 95 | 95 | 100 |

| Cost of living index | |
| Groceries index | |
| Health care index | |
| Housing index | |
| Transportation index | |
| Utilities index | |
| Lifestyle index | |
| Household index | |
| Educare index |
| Median Income | Per Year | Per Month | Max Budget (28% DTI) | Max Budget (36% DTI) |
| Owners | $76,754 | $6,396 | $1,791 | $2,303 |
| Renters | $52,629 | $4,386 | $1,228 | $1,579 |
| State | General Sales Tax | With Max Surtax |
| Missouri | 4.225% | 10.85% |
| State | Income Tax (Low) | Income Tax (High) |
| Missouri | 2% | 4.95% |
| City | Population | Cost of Living Index | National Avg. |
| Wheeling, MO | 210 | 77 | 23.0% |
| Breckenridge, MO | 504 | 78 | 22.4% |
| Hale, MO | 456 | 78 | 21.7% |
| Mooresville, MO | 138 | 79 | 21.0% |
| Braymer, MO | 678 | 79 | 20.6% |
| Chillicothe, MO | 9,377 | 84 | 15.8% |
| City | Population | Cost of Living Index | National Avg. |
| Yorkshire, VA | 9,373 | 120 | 20.1% |
| Seven Corners, VA | 9,382 | 135 | 34.7% |
| Summit View, WA | 9,371 | 125 | 25.5% |
| Comox Valley C (Puntledge - Black Creek), BC | 9,371 | n/a | |
| Coaldale, AB | 9,383 | n/a | |
| Chillicothe, MO | 9,377 | 84 | 15.8% |