| Index | Center | Missouri | National |
| Average Test Scores | 46% | 44% | 48% |
| Student/Teacher ratio | n/a | 14:1 | 16:1 |
| Total public schools | n/a | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
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| Index | Center | Missouri | National |
| Completed 8th grade | 72.0% | 86.0% | 84.3% |
| Completed high school | 68.9% | 84.2% | 83.0% |
| Completed some college | 23.3% | 57.7% | 59.4% |
| Completed associate degree | 11.8% | 35.2% | 38.5% |
| Completed bachelors | 8.4% | 27.6% | 30.3% |
| Completed masters | 1.7% | 10.4% | 11.5% |
| Completed professional degree | 1.4% | 2.8% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Center. Using the proficiency score averages, the average test scores for Center, MO schools is 46%. The average student to teacher ratio is n/a. In Center, MO, an average of 72.0% of students have completed 8th grade and an average of 68.9% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Frankford, MO | 464 | 70% | 45.8% |
| Monroe City, MO | 2,881 | 50% | 4.9% |
| Hannibal, MO | 17,980 | 49% | 2.3% |
| Vandalia, MO | 3,993 | 38% | 20.3% |
| Center, MO | 485 | 46% | 5.2% |
| City | Population | Avg. Test Scores | National Avg. |
| Creal Springs, IL | 485 | 42% | 12.5% |
| Nenahnezad, NM | 485 | 27% | 43.8% |
| Glasco, KS | 486 | 38% | 21.9% |
| Richfield, ID | 486 | 42% | 12.5% |
| Simpson, LA | 484 | 77% | 60.4% |
| Center, MO | 485 | 46% | 5.2% |
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