| Statistic | Reportedincidents | /100k people | Cairo/100k people | Missouri/100k people | National/100k people |
| Total crime | 0 | n/a (estimate) | 3,067 (estimate) | 2,554 | 2,281 |
| Murder | n/a | n/a | n/a | 9.1 | 5.7 |
| Rape | n/a | n/a | n/a | 46.4 | 38.0 |
| Robbery | n/a | n/a | n/a | 52.9 | 66.5 |
| Assault | n/a | n/a | n/a | 350.2 | 264.1 |
| Violent crime | n/a | n/a (estimate) | 551 (estimate) | 459 | 364 |
| Burglary | n/a | n/a | n/a | 251.2 | 250.7 |
| Theft | n/a | n/a | n/a | 1,365.4 | 1,347.2 |
| Vehicle theft | n/a | n/a | n/a | 478.6 | 318.7 |
| Property crime | n/a | n/a (estimate) | 2,516 (estimate) | 2,095 | 1,917 |


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| Item | Cairo | Missouri | National |
| Law enforcement employees (officers & civilians) | n/a | 12,115 | 558,732 |
| Police officers & civilians /1000 residents | n/a | 3.7 | 3.3 |
| State | Total offenders | Missouri /100K | National /100K |
| Missouri | 19,657 | 344 | 266 |
| City | Population | Violent crime/100k people | Property crime/100k people | Total crime/100k people |
| Huntsville, MO | 1,820 | 221 | 1,010 | 1,231 |
| Moberly, MO | 13,710 | 332 | 1,507 | 1,838 |
| Madison, MO | 422 | 633 | 2,887 | 3,519 |
| Renick, MO | 151 | 634 | 2,892 | 3,526 |
| Higbee, MO | 597 | 663 | 3,026 | 3,689 |
| Clifton Hill, MO | 76 | 679 | 3,100 | 3,780 |
| Jacksonville, MO | 134 | 742 | 3,386 | 4,127 |
| Cairo, MO | 230 | 551 | 2,516 | 3,067 |
| City | Population | Violent crime/100k people | Property crime/100k people | Total crime/100k people |
| Meadow Grove, NE | 230 | 308 | 2,645 | 2,953 |
| Tennyson, IN | 230 | 446 | 2,073 | 2,520 |
| Coleta, IL | 230 | 420 | 2,333 | 2,753 |
| South Carrollton, KY | 230 | 304 | 2,108 | 2,412 |
| Riggins, ID | 230 | 226 | 782 | 1,008 |
| Cairo, MO | 230 | 551 | 2,516 | 3,067 |