| Index | Big Pine Key | Florida | National |
| Average Test Scores | 83% | 55% | 48% |
| Student/Teacher ratio | 9:1 | 17:1 | 16:1 |
| Total public schools | 1 | 3,388 | 79,221 |
| Total private schools | n/a | 1,640 | 24,874 |
| Total post-secondary schools | n/a | 466 | 7,963 |

| Index | Big Pine Key | Florida | National |
| Completed 8th grade | 90.1% | 84.0% | 84.3% |
| Completed high school | 89.9% | 83.0% | 83.0% |
| Completed some college | 61.8% | 58.0% | 59.4% |
| Completed associate degree | 36.2% | 37.4% | 38.5% |
| Completed bachelors | 27.2% | 27.9% | 30.3% |
| Completed masters | 8.1% | 10.0% | 11.5% |
| Completed professional degree | 1.7% | 3.1% | 3.3% |
| Completed doctorate | 0.7% | 1.1% | 1.3% |
There are a total of 1 public schools, n/a private schools and n/a post-secondary schools in Big Pine Key. Using the proficiency score averages, the average test scores for Big Pine Key, FL schools is 83%. The average student to teacher ratio is 9:1. In Big Pine Key, FL, an average of 90.1% of students have completed 8th grade and an average of 89.9% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Big Pine Key, FL | 4,970 | 83% | 71.9% |
| City | Population | Avg. Test Scores | National Avg. |
| Farmington, ME | 4,969 | 41% | 15.3% |
| Tallassee, AL | 4,968 | 41% | 14.6% |
| Hamilton, MT | 4,973 | 43% | 11.5% |
| Wauchula, FL | 4,974 | 58% | 20.2% |
| Centreville, MD | 4,966 | 60% | 24.0% |
| Big Pine Key, FL | 4,970 | 83% | 71.9% |