| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 26°F | 50°F | 36°F | 3.2" |
| February | 29°F | 53°F | 40°F | 3.9" |
| March | 40°F | 65°F | 51°F | 6.0" |
| April | 48°F | 73°F | 59°F | 6.3" |
| May | 57°F | 81°F | 68°F | 8.4" |
| June | 69°F | 91°F | 79°F | 10.2" |
| July | 72°F | 95°F | 83°F | 7.1" |
| August | 70°F | 94°F | 81°F | 6.8" |
| September | 62°F | 86°F | 73°F | 5.2" |
| October | 50°F | 74°F | 61°F | 8.8" |
| November | 39°F | 62°F | 49°F | 5.4" |
| December | 28°F | 49°F | 37°F | 3.3" |
| Index | Isabella | Oklahoma | National |
| Air quality index | 48 | 55 | 42 |
| Pollution index | 286,399 | 1,271,533 | 2,726,193 |
| Measurement | Total |
| Days measured | 365 |
| Days with good air quality | 204 |
| Days with moderate air quality | 159 |
| Days w/ poor A.Q. for sensitive groups | 2 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.000% |
| Benzene | 0.004% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.004% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Meno, OK | 157 | 40 | 20.0% |
| Cleo Springs, OK | 413 | 40 | 20.0% |
| Ringwood, OK | 569 | 40 | 20.0% |
| Lahoma, OK | 489 | 40 | 20.0% |
| Okeene, OK | 998 | 48 | 4.0% |
| Isabella, OK | 91 | 48 | 4.0% |
| City | Population | Air Quality Index | National Avg. |
| Lowell Point, AK | 91 | 31 | 38.0% |
| Guion, AR | 91 | 36 | 28.0% |
| Hat Creek, CA | 91 | 42 | 16.0% |
| Lake Davis, CA | 91 | 44 | 12.0% |
| Peoria, CO | 91 | 58 | 16.0% |
| Isabella, OK | 91 | 48 | 4.0% |
Here are the best places to live in Oklahoma
These are the 10 most affordable cities in Oklahoma
See the best places to live in & around Isabella
10 best cities to buy a new house in Oklahoma