Compared to the other cities in Wisconsin and cities in all other U.S. states, how safe is Appleton, WI? From the gauges displayed above, you will notice that Appleton, WI has been ranked safer than 22% of other cities in the state of Wisconsin. In addition, Appleton, WI is safer than 45% of cities in the entire United States. To achieve these results, all Wisconsin and United States cities were analyzed to determine how many locations had a lower crime rate than Appleton, WI. By studying this data, it was possible to determine that Appleton, WI is below average in safety when compared with other United States cities.