| Index | Sisseton | South Dakota | National |
| Income per capita | $22,224 | $27,516 | $29,829 |
| Median household income | $38,516 | $52,078 | $55,322 |
| Median income owner occupied | $51,667 | $66,299 | $70,586 |
| Median income renter occupied | $30,643 | $30,800 | $35,192 |
| Median earnings male | $23,510 | $35,140 | $36,919 |
| Median earnings female | $24,279 | $24,451 | $26,250 |
| Unemployment rate | 4.0% | 2.8% | 4.7% |
| Poverty level | 20.0% | 14.0% | 15.1% |


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| Labour Type | Male | Female |
| Construction industry | 7.4% | 7.4% |
| Manufacturing sector | 37.5% | 37.5% |
| Financial & insurance services | 2.2% | 2.2% |
| Wholesale & retail services | 10.2% | 10.2% |
| Public administration | 6.6% | 6.6% |
| Transportation, warehousing & utilities | 0.9% | 0.9% |
| Education, health & social services | 6.7% | 6.7% |
| Other | 24.9% | 24.9% |
| City | Population | Household Income | National Avg. |
| Claire City, SD | 68 | $61,250 | 10.7% |
| Veblen, SD | 556 | $43,214 | 21.9% |
| Browns Valley, MN | 595 | $39,815 | 28.0% |
| New Effington, SD | 231 | $39,643 | 28.3% |
| Goodwill, SD | 696 | $38,846 | 29.8% |
| Sisseton, SD | 2,539 | $38,516 | 30.4% |
| City | Population | Household Income | National Avg. |
| Galva, IL | 2,539 | $44,191 | 20.1% |
| McLeansboro, IL | 2,539 | $55,714 | 0.7% |
| Madelia, MN | 2,539 | $52,386 | 5.3% |
| Colby, WI | 2,539 | $47,750 | 13.7% |
| Clinton, AR | 2,538 | $36,910 | 33.3% |
| Sisseton, SD | 2,539 | $38,516 | 30.4% |