| Statistic | Mound City | South Dakota | National |
| Population | 74 | 884,659 | 328,239,523 |
| Population density (sq mi) | 583 | 12 | 91 |
| Median age | 61.1 | 36.8 | 37.7 |
| Male/Female ratio | 1.5:1 | 1.0:1 | 1.0:1 |
| Married (15yrs & older) | 75% | 59% | 55% |
| Families w/ Kids under 18 | 20% | 44% | 43% |
| Speak English | 88% | 94% | 79% |
| Speak Spanish | 12% | 2% | 13% |
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| Race | Mound City | South Dakota | National |
| White | 89.19% | 84.77% | 73.35% |
| Black | 0.00% | 1.65% | 12.63% |
| Asian | 0.00% | 1.33% | 5.22% |
| American Indian | 4.05% | 8.72% | 0.82% |
| Native Hawaiian | 0.00% | 0.04% | 0.18% |
| Mixed race | 0.00% | 2.61% | 3.06% |
| Other race | 6.76% | 0.88% | 4.75% |
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