| Index | Knoxville | Iowa | National |
| Average Test Scores | 67% | 69% | 48% |
| Student/Teacher ratio | 14:1 | 13:1 | 16:1 |
| Total public schools | 6 | 1,101 | 79,221 |
| Total private schools | n/a | 208 | 24,874 |
| Total post-secondary schools | n/a | 96 | 7,963 |


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| Index | Knoxville | Iowa | National |
| Completed 8th grade | 87.3% | 89.2% | 84.3% |
| Completed high school | 85.5% | 87.7% | 83.0% |
| Completed some college | 50.1% | 59.8% | 59.4% |
| Completed associate degree | 24.1% | 38.4% | 38.5% |
| Completed bachelors | 15.9% | 27.2% | 30.3% |
| Completed masters | 5.4% | 8.7% | 11.5% |
| Completed professional degree | 1.2% | 2.7% | 3.3% |
| Completed doctorate | 0.0% | 1.1% | 1.3% |
There are a total of 6 public schools, n/a private schools and n/a post-secondary schools in Knoxville. Using the proficiency score averages, the average test scores for Knoxville, IA schools is 67%. The average student to teacher ratio is 14:1. In Knoxville, IA, an average of 87.3% of students have completed 8th grade and an average of 85.5% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Runnells, IA | 495 | 87% | 81.3% |
| Pella, IA | 10,526 | 84% | 75.6% |
| Monroe, IA | 1,848 | 78% | 63.0% |
| Pleasantville, IA | 2,201 | 73% | 51.7% |
| Lacona, IA | 346 | 62% | 29.2% |
| Knoxville, IA | 7,412 | 67% | 39.9% |
| City | Population | Avg. Test Scores | National Avg. |
| Richland, MS | 7,410 | 42% | 13.0% |
| Midland Park, NJ | 7,410 | 66% | 38.0% |
| North Vernon, IN | 7,415 | 44% | 9.0% |
| Kill Devil Hills, NC | 7,416 | 55% | 13.5% |
| Nappanee, IN | 7,418 | 63% | 31.3% |
| Knoxville, IA | 7,412 | 67% | 39.9% |