| Index | Desoto Lakes | Florida | National |
| Income per capita | $29,426 | $27,598 | $29,829 |
| Median household income | $67,414 | $48,900 | $55,322 |
| Median income owner occupied | $85,034 | $59,209 | $70,586 |
| Median income renter occupied | $42,259 | $34,622 | $35,192 |
| Median earnings male | $24,804 | $31,444 | $36,919 |
| Median earnings female | $33,722 | $25,332 | $26,250 |
| Unemployment rate | 3.1% | 4.9% | 4.7% |
| Poverty level | 3.6% | 16.1% | 15.1% |


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| Labour Type | Male | Female |
| Construction industry | 9.5% | 9.5% |
| Manufacturing sector | 2.7% | 2.7% |
| Financial & insurance services | 2.2% | 2.2% |
| Wholesale & retail services | 33.9% | 33.9% |
| Public administration | 0.0% | 0.0% |
| Transportation, warehousing & utilities | 0.0% | 0.0% |
| Education, health & social services | 27.3% | 27.3% |
| Other | 14.3% | 14.3% |
| City | Population | Household Income | National Avg. |
| Longboat Key, FL | 7,299 | $108,015 | 95.2% |
| Siesta Key, FL | 5,587 | $105,457 | 90.6% |
| Osprey, FL | 6,218 | $94,025 | 70.0% |
| Whitfield, FL | 4,398 | $87,264 | 57.7% |
| Lake Sarasota, FL | 4,148 | $84,112 | 52.0% |
| Desoto Lakes, FL | 1,907 | $67,414 | 21.9% |
| City | Population | Household Income | National Avg. |
| Mitchell, NE | 1,907 | $46,411 | 16.1% |
| Dawn-Euphemia, ON | 1,907 | n/a | |
| Swift Current No. 137, SK | 1,907 | n/a | |
| Joseph City, AZ | 1,908 | $64,979 | 17.5% |
| Harwich Port, MA | 1,906 | $62,794 | 13.5% |
| Desoto Lakes, FL | 1,907 | $67,414 | 21.9% |