| Index | Chamberlain | South Dakota | National |
| Income per capita | $51,786 | $41,166 | $44,883 |
| Median household income | $75,241 | $77,914 | $81,333 |
| Median income owner occupied | $93,629 | $100,475 | $106,172 |
| Median income renter occupied | $46,181 | $45,187 | $52,080 |
| Median earnings male | $58,854 | $52,540 | $54,343 |
| Median earnings female | $43,689 | $36,073 | $38,439 |
| Unemployment rate | 1.9% | 2.9% | 4.9% |
| Poverty level | 16.3% | 14.0% | 15.1% |


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| Labour Type | Male | Female |
| Construction industry | 3.2% | 3.2% |
| Manufacturing sector | 0.0% | 0.0% |
| Financial & insurance services | 6.5% | 6.5% |
| Wholesale & retail services | 6.0% | 6.0% |
| Public administration | 21.6% | 21.6% |
| Transportation, warehousing & utilities | 3.9% | 3.9% |
| Education, health & social services | 26.2% | 26.2% |
| Other | 30.2% | 30.2% |
| City | Population | Household Income | National Avg. |
| Oacoma, SD | 384 | $98,269 | 20.8% |
| Pukwana, SD | 365 | $89,692 | 10.3% |
| Reliance, SD | 113 | $81,554 | 0.3% |
| Ola, SD | 0 | $0 | 100.0% |
| Chamberlain, SD | 2,637 | $75,241 | 7.5% |
| City | Population | Household Income | National Avg. |
| Forsyth, MO | 2,637 | $55,119 | 32.2% |
| Alden, NY | 2,637 | $88,287 | 8.6% |
| Odell, OR | 2,637 | $110,529 | 35.9% |
| Imperial, PA | 2,637 | $83,632 | 2.8% |
| Brookville, IN | 2,636 | $55,651 | 31.6% |
| Chamberlain, SD | 2,637 | $75,241 | 7.5% |