| Index | Santee | South Carolina | National |
| Median home price | $113,200 | $143,600 | $184,700 |
| Median rent asked | $751 | $811 | $949 |
| Avg. people per household | 2.9 | 2.6 | 2.6 |
| Owner occupied households | 55.2% | 68.4% | 63.6% |
| Renter occupied households | 44.8% | 31.6% | 36.4% |
| Index | Santee | South Carolina | National |
| Zillow home value index | n/a | $144,600 | $196,500 |
| Year over year appreciation rate | n/a | 7.27% | 6.79% |
| 5 year average appreciation rate | n/a | 3.66% | 5.28% |
| 10 year average appreciation rate | n/a | 0.49% | 0.01% |
| City, State | Population | Home Price | National Avg. |
| Vance, SC | 101 | $74,000 | 60% |
| Eutawville, SC | 325 | $80,500 | 56% |
| Summerton, SC | 1,013 | $102,100 | 45% |
| Bowman, SC | 809 | $103,600 | 44% |
| Elloree, SC | 721 | $105,900 | 43% |
| Santee, SC | 1,184 | $113,200 | 39% |
| City, State | Population | Home Price | National Avg. |
| Glenns Ferry, ID | 1,184 | $91,500 | 50% |
| Buxton, NC | 1,184 | $230,000 | 25% |
| Loganville, PA | 1,184 | $192,600 | 4% |
| Thomas, OK | 1,184 | $71,500 | 61% |
| Tilden, NE | 1,184 | $67,900 | 63% |
| Santee, SC | 1,184 | $113,200 | 39% |