Santa Cruz, NM has a population of 350 and is the 21,619th largest city in the United States. The population density is 540 per sq mi which is 3053% higher than the New Mexico average and 496% higher than the national average. The median age in Santa Cruz is 32 which is approximately 13% lower than the New Mexico average of 37. In Santa Cruz, 51% of the population over 15 years of age are married, 36% speak English and 64% speak Spanish. 79% of Santa Cruz residents were born in New Mexico, 14% were born out of state, 0% were born outside of the United States and 7% were foreign born.