McLain, MS has a population of 384 and is the 21,085th largest city in the United States. The population density is 113 per sq mi which is 79% higher than the Mississippi average and 25% higher than the national average. The median age in McLain is 44 which is approximately 21% higher than the Mississippi average of 36. In McLain, 46% of the population over 15 years of age are married, 100% speak English and 0% speak Spanish. 84% of McLain residents were born in Mississippi, 16% were born out of state, 0% were born outside of the United States and 0% were foreign born.