Holyoke, MA has a population of 40,079 and is the 1,007th largest city in the United States. The population density is 1,883 per sq mi which is 124% higher than the Massachusetts average and 1979% higher than the national average. The median age in Holyoke is 36 which is approximately 9% lower than the Massachusetts average of 39. In Holyoke, 40% of the population over 15 years of age are married, 56% speak English and 39% speak Spanish. 55% of Holyoke residents were born in Massachusetts, 17% were born out of state, 22% were born outside of the United States and 6% were foreign born.